The aim of this educational curriculum is to present and evaluate latest breakthroughs, therapies, and strategies in Breast Cancer (BC) management that have transformed the approach to this complex and chronic condition. The two self-study modules are designed to offer a thorough understanding of the wide range of treatment modalities available. From conventional methods to cutting-edge innovations, providing insights on BC management optimization, including the use of Antibody Drug Conjugates (ADCs), immunotherapy, Parp-inhibitors and a potential therapeutic algorithm for HER2-low breast cancer.